Pioneering Impurity Solutions
We specialize in the identification, isolation, and synthesis of process-related impurities. Our expertise extends to a wide array of impurities, including isomeric impurities, degradation impurities, metabolites, and glucuronides.
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Product Data
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Technical Data
Chemical Name : 3-((3-chloro-4-fluorophenyl)(6-((E)-4-(dimethylamino)but-2-enamido)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-yl)amino)-4-(dimethylamino)butanoic acid
Smiles : FC(C=C1)=C(Cl)C=C1N(C(CC(O)=O)CN(C)C)C2=NC=NC3=CC(O[C@H]4CCOC4)=C(NC(/C=C/CN(C)C)=O)C=C32
Synonym : 1-[2-[[(2RS)-oxiranyl]methoxy]phenyl]-3-phenylpropan-1-one,
Related Products
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003379_afatinib_350.jpg)
Afatinib
CAT No: o2h-A026000
CAS No: 850140-72-6
Mol.F. : C24H25ClFN5O3
Mol.Wt. : 486
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003382_afatinib-impurity-c_350.jpg)
Afatinib Impurity C
CAT No: o2h-A026003
CAS No: 945553-91-3
Mol.F. : C24H25ClFN5O3
Mol.Wt. : 486
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003381_afatinib-impurity-b_350.jpg)
Afatinib Impurity B
CAT No: o2h-A026002
CAS No: 314771-76-1
Mol.F. : C18H16ClFN4O2
Mol.Wt. : 374.8
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003380_afatinib-impurity-a_350.jpg)
Afatinib Impurity A
CAT No: o2h-A026001
CAS No: 402855-07-6
Mol.F. : C18H14ClFN4O4
Mol.Wt. : 404.8
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003384_afatinib-impurity-e_350.jpg)
Afatinib Impurity E
CAT No: o2h-A026005
CAS No: N/A
Mol.F. : C24H25Cl2N5O3
Mol.Wt. : 502.4
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003383_afatinib-impurity-d_350.jpg)
Afatinib Impurity D
CAT No: o2h-A026004
CAS No: 1680184-59-1
Mol.F. : C24H25ClFN5O3
Mol.Wt. : 486
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003386_afatinib-impurity-g_350.jpg)
Afatinib Impurity G
CAT No: o2h-A026007
CAS No: N/A
Mol.F. : C24H25ClFN5O3
Mol.Wt. : 486
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003385_afatinib-impurity-f_350.jpg)
Afatinib Impurity F
CAT No: o2h-A026006
CAS No: N/A
Mol.F. : C24H25F2N5O3
Mol.Wt. : 469.5
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003388_afatinib-impurity-i_350.jpg)
Afatinib Impurity I
CAT No: o2h-A026009
CAS No: N/A
Mol.F. : C22H19BrClFN4O3
Mol.Wt. : 521.8
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003387_afatinib-impurity-h_350.jpg)
Afatinib Impurity H
CAT No: o2h-A026008
CAS No: N/A
Mol.F. : C22H20ClFN4O3
Mol.Wt. : 442.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003391_afatinib-n-oxide_350.jpg)
Afatinib N-Oxide
CAT No: o2h-A026012
CAS No: N/A
Mol.F. : C24H25ClFN5O4
Mol.Wt. : 501.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003390_afatinib-impurity-k_350.jpg)
Afatinib Impurity K
CAT No: o2h-A026011
CAS No: N/A
Mol.F. : C23H23ClFN5O3
Mol.Wt. : 472
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003389_afatinib-impurity-j_350.jpg)
Afatinib Impurity J
CAT No: o2h-A026010
CAS No: 1456696-14-2
Mol.F. : C18H22N4O4
Mol.Wt. : 358.4
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003392_afatinib-dimaleate_350.jpg)
Afatinib Dimaleate
CAT No: o2h-A026013
CAS No: 850140-73-7
Mol.F. : C24H25ClFN5O3 . C8H8O8
Mol.Wt. : 485.9 232.1
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003395_afatinib-butoxy-analog_350.jpg)
Afatinib Butoxy Analog
CAT No: o2h-A026016
CAS No: N/A
Mol.F. : C24H27ClFN5O2
Mol.Wt. : 472
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003394_afatinib-hydroxy-impurity_350.jpg)
Afatinib Impurity 32
CAT No: o2h-A026015
CAS No: 2223677-58-3
Mol.F. : C22H20ClFN4O4
Mol.Wt. : 458.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003393_afatinib-sulfonic-acid-analog_350.jpg)
Afatinib Sulfonic Acid Analog
CAT No: o2h-A026014
CAS No: 2283295-16-7
Mol.F. : C24H27ClFN5O6S
Mol.Wt. : 568
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003397_afatinib-impurity-3_350.jpg)
Afatinib Impurity 3
CAT No: o2h-A026018
CAS No: 2475094-96-1
Mol.F. : C14H7ClF2N4O2
Mol.Wt. : 336.7
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003396_afatinib-impurity-2_350.jpg)
Afatinib Impurity 2
CAT No: o2h-A026017
CAS No: 2475094-95-0
Mol.F. : C14H8ClFN4O3
Mol.Wt. : 334.7
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003398_afatinib-impurity-4_350.jpg)
Afatinib Impurity 4
CAT No: o2h-A026019
CAS No: 2512206-82-3
Mol.F. : C14H7Cl2FN4O2
Mol.Wt. : 353.1
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003400_afatinib-impurity-6_350.jpg)
Afatinib Impurity 6
CAT No: o2h-A026021
CAS No: N/A
Mol.F. : C18H17FN4O2
Mol.Wt. : 340.4
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003399_afatinib-impurity-5_350.jpg)
Afatinib Impurity 5
CAT No: o2h-A026020
CAS No: 179552-74-0
Mol.F. : C15H10ClFN4O3
Mol.Wt. : 348.7
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003402_afatinib-impurity-8_350.jpg)
Afatinib Impurity 8
CAT No: o2h-A026023
CAS No: N/A
Mol.F. : C18H17ClN4O2
Mol.Wt. : 356.8
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003401_afatinib-impurity-7_350.jpg)
Afatinib Impurity 7
CAT No: o2h-A026022
CAS No: N/A
Mol.F. : C18H18N4O2
Mol.Wt. : 322.4
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003404_afatinib-impurity-10_350.jpg)
Afatinib Impurity 10
CAT No: o2h-A026025
CAS No: N/A
Mol.F. : C48H50Cl2F2N10O6
Mol.Wt. : 971.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003407_afatinib-impurity-13_350.jpg)
Afatinib Impurity 13
CAT No: o2h-A026028
CAS No: 2413212-19-6
Mol.F. : C22H20ClFN4O4
Mol.Wt. : 458.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003406_afatinib-impurity-12_350.jpg)
Afatinib Impurity 12
CAT No: o2h-A026027
CAS No: 2121530-37-6
Mol.F. : C22H20ClFN4O4
Mol.Wt. : 458.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003405_afatinib-impurity-11_350.jpg)
Afatinib Impurity 11
CAT No: o2h-A026026
CAS No: 2413212-17-4
Mol.F. : C22H20ClFN4O3
Mol.Wt. : 442.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003408_afatinib-impurity-14_350.jpg)
Afatinib Impurity 14
CAT No: o2h-A026029
CAS No: 2413212-21-0
Mol.F. : C24H27ClFN5O4
Mol.Wt. : 504
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003411_afatinib-impurity-17_350.jpg)
Afatinib Impurity 17
CAT No: o2h-A026032
CAS No: N/A
Mol.F. : C21H22ClFN5O2
Mol.Wt. : 430.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003410_afatinib-impurity-16_350.jpg)
Afatinib Impurity 16
CAT No: o2h-A026031
CAS No: N/A
Mol.F. : C19H16ClFN4O3
Mol.Wt. : 402.8
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003409_afatinib-impurity-15_350.jpg)
Afatinib Impurity 15
CAT No: o2h-A026030
CAS No: 2413212-23-2
Mol.F. : C24H27ClFN5O4
Mol.Wt. : 504
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003412_afatinib-impurity-18_350.jpg)
Afatinib Impurity 18
CAT No: o2h-A026033
CAS No: 2413212-25-4
Mol.F. : C24H26FN5O3
Mol.Wt. : 451.5
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003415_afatinib-impurity-21_350.jpg)
Afatinib Impurity 21
CAT No: o2h-A026036
CAS No: 2044709-72-8
Mol.F. : C18H16F2N4O2
Mol.Wt. : 358.4
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003414_afatinib-impurity-20_350.jpg)
Afatinib Impurity 20
CAT No: o2h-A026035
CAS No: 1957132-02-3
Mol.F. : C22H23ClFN5O2
Mol.Wt. : 443.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003413_afatinib-impurity-19_350.jpg)
Afatinib Impurity 19
CAT No: o2h-A026034
CAS No: 1245555-42-3
Mol.F. : C21H21ClFN5O2
Mol.Wt. : 429.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003417_afatinib-impurity-23_350.jpg)
Afatinib Impurity 23
CAT No: o2h-A026038
CAS No: 2475095-50-0
Mol.F. : C14H7ClF2N4O2
Mol.Wt. : 336.7
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003416_afatinib-impurity-22_350.jpg)
Afatinib Impurity 22
CAT No: o2h-A026037
CAS No: N/A
Mol.F. : C20H18ClFN4O3
Mol.Wt. : 416.8
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003420_afatinib-impurity-26_350.jpg)
Afatinib Impurity 26
CAT No: o2h-A026041
CAS No: 314771-88-5
Mol.F. : C18H14ClFN4O4
Mol.Wt. : 404.8
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003419_afatinib-impurity-25_350.jpg)
Afatinib Impurity 25
CAT No: o2h-A026040
CAS No: 212776-19-7
Mol.F. : C7H13NO2
Mol.Wt. : 143.2
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003418_afatinib-impurity-24_350.jpg)
Afatinib Impurity 24
CAT No: o2h-A026039
CAS No: 1255078-56-8
Mol.F. : C8H15NO2 : HCl
Mol.Wt. : 157.2 : 36.5
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003422_afatinib-impurity-28_350.jpg)
Afatinib Impurity 28
CAT No: o2h-A026043
CAS No: N/A
Mol.F. : C22H20ClFN4O4
Mol.Wt. : 458.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003421_afatinib-impurity-27_350.jpg)
Afatinib Impurity 27
CAT No: o2h-A026042
CAS No: 618061-76-0
Mol.F. : C24H27ClFN4O6P
Mol.Wt. : 552.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0026405_afatinib-impurity-31_350.jpg)
Afatinib Impurity 31
CAT No: o2h-A026046
CAS No: 2223677-58-3
Mol.F. : C22H20ClFN4O4
Mol.Wt. : 458.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003424_afatinib-impurity-30_350.jpg)
Afatinib Impurity 30
CAT No: o2h-A026045
CAS No: 501332-25-8
Mol.F. : C7H13NO2
Mol.Wt. : 143.2
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0003423_afatinib-impurity-29_350.jpg)
Afatinib Impurity 29
CAT No: o2h-A026044
CAS No: N/A
Mol.F. : C22H23ClFN4O6P
Mol.Wt. : 524.9
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0031298_afatinib-impurity-ii-formyl-impurity_350.jpg)
Afatinib Impurity-II (Formyl impurity)
CAT No: o2h-A026048
CAS No: NA
Mol.F. : C19H16ClFN4O3
Mol.Wt. : 402.81
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0031297_afatinib-impurity-i-cyclized-impurity_350.jpg)
Afatinib Impurity-I (Cyclized impurity)
CAT No: o2h-A026047
CAS No: NA
Mol.F. : C22H20ClFN4O4
Mol.Wt. : 458.87
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0031300_afatinib-impurity-v-hydroxy-impurity_350.jpg)
Afatinib Impurity-V (Hydroxy impurity)
CAT No: o2h-A026050
CAS No: NA
Mol.F. : C20H19ClFN5O2
Mol.Wt. : 415.84
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0031299_afatinib-impurity-iii-stage-ii-intermediate_350.jpg)
Afatinib Impurity-III (Stage-II intermediate)
CAT No: o2h-A026049
CAS No: NA
Mol.F. : C18H16ClFN4O2
Mol.Wt. : 374.79
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0031302_afatinib-impurity-vii-dichloro-impurity_350.jpg)
Afatinib Impurity-VII (Dichloro impurity)
CAT No: o2h-A026052
CAS No: NA
Mol.F. : C24H25Cl2N5O3
Mol.Wt. : 502.39
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0031301_afatinib-impurity-vi-difluoro-impurity_350.jpg)
Afatinib Impurity-VI (Difluoro impurity)
CAT No: o2h-A026051
CAS No: NA
Mol.F. : C24H25F2N5O3
Mol.Wt. : 469.48
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0031303_afatinib-impurity-viii-crotonamide-impurity_350.jpg)
Afatinib Impurity-VIII (Crotonamide impurity)
CAT No: o2h-A026053
CAS No: NA
Mol.F. : C22H20ClFN4O3
Mol.Wt. : 442.87
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0031305_afatinib-impurity-x-dma-impurity_350.jpg)
Afatinib Impurity-X (DMA impurity)
CAT No: o2h-A026055
CAS No: NA
Mol.F. : C22H21ClFN5O4
Mol.Wt. : 473.88
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0031304_afatinib-impurity-ix-dimer-impurity_350.jpg)
Afatinib Impurity-IX (Dimer impurity)
CAT No: o2h-A026054
CAS No: NA
Mol.F. : C38H30Cl2F2N8O6
Mol.Wt. : 803.59
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0031307_afatinib-r-isomer_350.jpg)
Afatinib R-Isomer
CAT No: o2h-A026057
CAS No: NA
Mol.F. : C24H25ClFN5O3
Mol.Wt. : 485.93
![molecule-image](https://o2hdiscovery.co/wp-content/uploads/2023/12/0031306_afatinib-impurity-iv-ksm-iii_350.jpg)
Afatinib Impurity-IV (KSM-III)
CAT No: o2h-A026056
CAS No: NA
Mol.F. : C6H12ClNO2
Mol.Wt. : 165.61