Pioneering Impurity Solutions
We specialize in the identification, isolation, and synthesis of process-related impurities. Our expertise extends to a wide array of impurities, including isomeric impurities, degradation impurities, metabolites, and glucuronides.
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Product Data
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Technical Data
Chemical Name : 6-chloro-1H-imidazo[4,5-b]pyrazine
Smiles : ClC1=CN=C2C(NC=N2)=N1
Synonym : N/A
Related Products
Tofacitinib Keto Impurity
CAT No: o2h-T066057
CAS No: 1236267-27-8
Mol.F. : C16H20N6O2
Mol.Wt. : 328.4
Tofacitinib Citrate
CAT No: o2h-T066001
CAS No: 540737-29-9
Mol.F. : C16H20N6O : C6H8O7
Mol.Wt. : 312.4 : 192.1
Tofacitinib
CAT No: o2h-T066000
CAS No: 477600-75-2
Mol.F. : C16H20N6O
Mol.Wt. : 312.4
Tofacitinib Impurity C Citrate
CAT No: o2h-T066004
CAS No: 2174011-55-1
Mol.F. : C16H20N6O. C6H8O7
Mol.Wt. : 312.4 : 192.1
Tofacitinib Impurity B
CAT No: o2h-T066003
CAS No: 1092578-48-7
Mol.F. : C16H20N6O
Mol.Wt. : 312.4
Tofacitinib Impurity A
CAT No: o2h-T066002
CAS No: 1092578-46-5
Mol.F. : C16H20N6O
Mol.Wt. : 312.4
Tofacitinib Impurity F
CAT No: o2h-T066005
CAS No: 384338-23-2
Mol.F. : C14H22N2
Mol.Wt. : 218.3
Tofacitinib Impurity K
CAT No: o2h-T066008
CAS No: 2328165-36-0
Mol.F. : C16H21N5O3
Mol.Wt. : 331.4
Tofacitinib Impurity J
CAT No: o2h-T066007
CAS No: N/A
Mol.F. : C14H22N2 : 2(HCl)
Mol.Wt. : 218.3 : 2(36.5)
Tofacitinib Impurity I
CAT No: o2h-T066006
CAS No: N/A
Mol.F. : C14H22N2 : 2(HCl)
Mol.Wt. : 218.3 : 2(36.5)
Tofacitinib Impurity L
CAT No: o2h-T066009
CAS No: 1675248-19-7
Mol.F. : C16H22N6O2
Mol.Wt. : 330.4
Tofacitinib Impurity O
CAT No: o2h-T066012
CAS No: 477600-73-0
Mol.F. : C20H25N5
Mol.Wt. : 335.5
Tofacitinib Impurity N
CAT No: o2h-T066011
CAS No: 1260614-73-0
Mol.F. : C13H19N5
Mol.Wt. : 245.3
Tofacitinib Impurity M
CAT No: o2h-T066010
CAS No: 477600-74-1
Mol.F. : C13H19N5
Mol.Wt. : 245.3
Tofacitinib Impurity Q
CAT No: o2h-T066014
CAS No: 3680-69-1
Mol.F. : C6H4ClN3
Mol.Wt. : 153.6
Tofacitinib Impurity P
CAT No: o2h-T066013
CAS No: 1252883-90-1
Mol.F. : C20H25N5
Mol.Wt. : 335.5
Tofacitinib Impurity R
CAT No: o2h-T066015
CAS No: 479633-63-1
Mol.F. : C13H10ClN3O2S
Mol.Wt. : 307.8
Tofacitinib Impurity U
CAT No: o2h-T066018
CAS No: 1616760-97-4
Mol.F. : C13H18ClN5
Mol.Wt. : 297.8
Tofacitinib Impurity T
CAT No: o2h-T066017
CAS No: 2504210-31-3
Mol.F. : C16H18N6O
Mol.Wt. : 310.4
Tofacitinib Impurity S
CAT No: o2h-T066016
CAS No: 923036-30-0
Mol.F. : C27H31N5O2S
Mol.Wt. : 489.6
Tofacitinib Impurity V
CAT No: o2h-T066019
CAS No: 1616761-00-2
Mol.F. : C16H19ClN6O
Mol.Wt. : 346.8
Tofacitinib Impurity W
CAT No: o2h-T066020
CAS No: 2504210-32-4
Mol.F. : C13H18ClN5
Mol.Wt. : 279.8
Tofacitinib Impurity X
CAT No: o2h-T066021
CAS No: 2097982-05-1
Mol.F. : C13H19N5
Mol.Wt. : 245.3
Tofacitinib Related Compound 1
CAT No: o2h-T066024
CAS No: 2504210-30-2
Mol.F. : C16H22N6O2
Mol.Wt. : 330.4
Tofacitinib Impurity Z
CAT No: o2h-T066023
CAS No: 477600-76-3
Mol.F. : C15H21N5O
Mol.Wt. : 287.4
Tofacitinib Impurity Y
CAT No: o2h-T066022
CAS No: 2227197-38-6
Mol.F. : C14H21N5
Mol.Wt. : 259.4
Tofacitinib Related Compound 2 HCl
CAT No: o2h-T066025
CAS No: 1640971-87-4
Mol.F. : C10H17N3O : HCl
Mol.Wt. : 195.3 : 36.5
Tofacitinib Related Compound 8
CAT No: o2h-T066029
CAS No: 2504210-41-5
Mol.F. : C29H38N10O2
Mol.Wt. : 558.7
Tofacitinib Related Compound 6
CAT No: o2h-T066028
CAS No: 2459302-77-1
Mol.F. : C19H21N7O2
Mol.Wt. : 379.4
Tofacitinib Related Compound 4
CAT No: o2h-T066027
CAS No: 1092578-43-2
Mol.F. : C16H20N6O
Mol.Wt. : 312.4
Tofacitinib Related Compound 3
CAT No: o2h-T066026
CAS No: N/A
Mol.F. : C13H18N4O2
Mol.Wt. : 262.3
Tofacitinib Related Compound 11
CAT No: o2h-T066032
CAS No: 1640971-60-3
Mol.F. : C14H20N6O
Mol.Wt. : 288.4
Tofacitinib Related Compound 10
CAT No: o2h-T066031
CAS No: 2374700-39-5
Mol.F. : C13H19N5
Mol.Wt. : 245.3
Tofacitinib Related Compound 9
CAT No: o2h-T066030
CAS No: 2459302-78-2
Mol.F. : C34H45N7
Mol.Wt. : 551.8
Tofacitinib Related Compound 13
CAT No: o2h-T066034
CAS No: 1092578-45-4
Mol.F. : C20H25N5
Mol.Wt. : 335.5
Tofacitinib Related Compound 12
CAT No: o2h-T066033
CAS No: 2459302-80-6
Mol.F. : C20H25N5
Mol.Wt. : 335.5
Tofacitinib Related Compound 15
CAT No: o2h-T066036
CAS No: N/A
Mol.F. : C15H21N5O
Mol.Wt. : 287.4
Tofacitinib Related Compound 14
CAT No: o2h-T066035
CAS No: 2227199-28-0
Mol.F. : C14H19N5O
Mol.Wt. : 273.3
Tofacitinib Related Compound 18
CAT No: o2h-T066039
CAS No: 1092578-44-3
Mol.F. : C27H31N5O2S
Mol.Wt. : 489.6
Tofacitinib Related Compound 17
CAT No: o2h-T066038
CAS No: 2056104-91-5
Mol.F. : C27H31N5O2S
Mol.Wt. : 489.6
Tofacitinib Related Compound 16
CAT No: o2h-T066037
CAS No: N/A
Mol.F. : C15H23N5
Mol.Wt. : 273.4
Tofacitinib Related Compound 21
CAT No: o2h-T066042
CAS No: 1809002-40-1
Mol.F. : C16H22N6O : C6H8O7
Mol.Wt. : 314.4 : 192.1
Tofacitinib Related Compound 20
CAT No: o2h-T066041
CAS No: 2259288-22-5
Mol.F. : C23H26N6O3S
Mol.Wt. : 466.6
Tofacitinib Related Compound 19
CAT No: o2h-T066040
CAS No: 2028267-73-2
Mol.F. : C16H20N6O2
Mol.Wt. : 328.4
Tofacitinib Related Compound 24
CAT No: o2h-T066044
CAS No: 2459302-82-8
Mol.F. : C19H23N7O2
Mol.Wt. : 381.4
Tofacitinib Related Compound 23 DiHCl
CAT No: o2h-T066043
CAS No: N/A
Mol.F. : C13H21N5.2 HCl
Mol.Wt. : 247.4 : 2(36.5)
Tofacitinib Related Compound 27
CAT No: o2h-T066047
CAS No: N/A
Mol.F. : C13H18N4O2
Mol.Wt. : 262.3
Tofacitinib Related Compound 26 HCl
CAT No: o2h-T066046
CAS No: 1206824-85-2
Mol.F. : C10H17N3O : HCl
Mol.Wt. : 195.3 : 36.5
Tofacitinib Related Compound 25
CAT No: o2h-T066045
CAS No: 2504210-33-5
Mol.F. : C27H31N5OS
Mol.Wt. : 473.7
Tofacitinib Related Compound 29
CAT No: o2h-T066049
CAS No: 134965-85-8
Mol.F. : C12H7ClN6
Mol.Wt. : 270.7
Tofacitinib Related Compound 28 (rac-trans-Tofacitinib)
CAT No: o2h-T066048
CAS No: N/A
Mol.F. : C16H20N6O
Mol.Wt. : 312.4
Tofacitinib Related Impurity (PF-05579970)
CAT No: o2h-T066050
CAS No: N/A
Mol.F. : C15H21N5O
Mol.Wt. : 287.4
Tofacitinib Impurity (N-Des-(2-Cyanide-acetyl)-(3S,4R))
CAT No: o2h-T066052
CAS No: 2378663-15-9
Mol.F. : C13H19N5
Mol.Wt. : 245.3
rac-Tofacitinib (Mixture of Diastereomers)
CAT No: o2h-T066051
CAS No: 344418-92-4
Mol.F. : C16H20N6O
Mol.Wt. : 312.4
Tofacitinib Impurity (N-Des-(2-Cyanide-acetyl)-(3R,4S))
CAT No: o2h-T066053
CAS No: 2459302-75-9
Mol.F. : C13H19N5
Mol.Wt. : 245.3
Tofacitinib N-hydroxy Impurity
CAT No: o2h-T066054
CAS No: 2459302-76-0
Mol.F. : C13H19N5O
Mol.Wt. : 261.3
7-Deazapurine
CAT No: o2h-T066056
CAS No: 271-70-5
Mol.F. : C6H7N3
Mol.Wt. : 121.1
1-Benzyl-4-methylpiperidin-3-one
CAT No: o2h-T066055
CAS No: 32018-96-5
Mol.F. : C13H17NO
Mol.Wt. : 203.3
Tofacitinib Citrate Recamic Mixture
CAT No: o2h-T066059
CAS No: N/A
Mol.F. : C16H20N6O
Mol.Wt. : 312.4
Tofacitinib Hydroxy Impurity
CAT No: o2h-T066058
CAS No: N/A
Mol.F. : C16H20N6O2
Mol.Wt. : 328.4
Tofacitinib Mixure of Diastereomers
CAT No: o2h-T066060
CAS No: 2664002-63-3
Mol.F. : C16H20N6O : C6H8O7
Mol.Wt. : 312.4 : 192.1
Tofacitinib Related Substance 2
CAT No: o2h-T066063
CAS No: 2101951-13-5
Mol.F. : C16H22N6O3
Mol.Wt. : 346.4
Tofacitinib Related Substance 1
CAT No: o2h-T066062
CAS No: 2101958-24-9
Mol.F. : C16H22N6O3
Mol.Wt. : 346.4
Tofacitinib Diastereomer 1 and 2
CAT No: o2h-T066061
CAS No: N/A
Mol.F. : C16H20N6O : C6H8O7
Mol.Wt. : 312.4 : 192.1
Tofacitinib Related Substance 4
CAT No: o2h-T066064
CAS No: N/A
Mol.F. : C18H26N6O2
Mol.Wt. : 358.4
Tofacitinib Dihydro Impurity
CAT No: o2h-T066067
CAS No: 1640972-35-5
Mol.F. : C16H22N6O
Mol.Wt. : 314.4
Tofacitinib Related Substance 6
CAT No: o2h-T066066
CAS No: N/A
Mol.F. : C16H22N6O4
Mol.Wt. : 362.4
Tofacitinib Related Substance 5
CAT No: o2h-T066065
CAS No: N/A
Mol.F. : C16H22N6O2
Mol.Wt. : 330.4
Tofacitinib Related Substance 9
CAT No: o2h-T066069
CAS No: N/A
Mol.F. : C21H27N7O3
Mol.Wt. : 425.5
Tofacitinib Related Substance 8
CAT No: o2h-T066068
CAS No: 2101951-20-4
Mol.F. : C16H20N6O2
Mol.Wt. : 328.4
Tofacitinib Related Substance 11
CAT No: o2h-T066071
CAS No: N/A
Mol.F. : C16H19ClN6O
Mol.Wt. : 346.8
Tofacitinib Related Substance 10
CAT No: o2h-T066070
CAS No: N/A
Mol.F. : C32H40N12O2
Mol.Wt. : 624.8
Tofacitinib Impurity 4
CAT No: o2h-T066074
CAS No: 1675248-18-6
Mol.F. : C18H25N5O3
Mol.Wt. : 359.4
Tofacitinib Impurity 3
CAT No: o2h-T066073
CAS No: 1206825-36-6
Mol.F. : C13H19N5
Mol.Wt. : 245.3
Tofacitinib Impurity 2
CAT No: o2h-T066072
CAS No: 1640971-51-2
Mol.F. : C16H20N6O2
Mol.Wt. : 328.4
Tofacitinib Impurity 5
CAT No: o2h-T066075
CAS No: 1354621-59-2
Mol.F. : C14H22N2
Mol.Wt. : 218.3
Tofacitinib Impurity 8
CAT No: o2h-T066078
CAS No: 1527525-58-1
Mol.F. : C15H18N6O
Mol.Wt. : 298.4
Tofacitinib Impurity 7
CAT No: o2h-T066077
CAS No: N/A
Mol.F. : C13H19N5
Mol.Wt. : 245.3
Tofacitinib Impurity 6
CAT No: o2h-T066076
CAS No: N/A
Mol.F. : C19H22N8
Mol.Wt. : 362.4
Tofacitinib Impurity 9
CAT No: o2h-T066079
CAS No: 2382711-65-9
Mol.F. : C34H42N10O2
Mol.Wt. : 622.8
Tofacitinib Impurity 28
CAT No: o2h-T066081
CAS No: 2227199-31-5
Mol.F. : C20H29N5O3
Mol.Wt. : 387.5
Tofacitinib Impurity 27
CAT No: o2h-T066080
CAS No: N/A
Mol.F. : C23H34N6O3
Mol.Wt. : 442.6
Tofacitinib Impurity 31
CAT No: o2h-T066084
CAS No: 344418-61-7
Mol.F. : C15H21N5O
Mol.Wt. : 287.4
Tofacitinib Impurity 30
CAT No: o2h-T066083
CAS No: 105-56-6
Mol.F. : C5H7NO2
Mol.Wt. : 113.1
Tofacitinib Impurity 29
CAT No: o2h-T066082
CAS No: N/A
Mol.F. : C21H27N7O3
Mol.Wt. : 425.5
Tofacitinib Impurity 32
CAT No: o2h-T066085
CAS No: 477600-69-4
Mol.F. : C14H22N2
Mol.Wt. : 218.3
Tofacitinib Impurity 33
CAT No: o2h-T066086
CAS No: 16372-08-0
Mol.F. : C6H6ClN3
Mol.Wt. : 155.6
Tofacitinib Impurity 36
CAT No: o2h-T066089
CAS No: N/A
Mol.F. : C16H20N6O2
Mol.Wt. : 328.4
Tofacitinib Impurity 35
CAT No: o2h-T066088
CAS No: 1092578-47-6
Mol.F. : C16H20N6O
Mol.Wt. : 312.4
Tofacitinib -Dihydro Intermediate
CAT No: o2h-T066091
CAS No: NA
Mol.F. : C13H21N5
Mol.Wt. : 247.35
Tofacitinib Impurity 40
CAT No: o2h-T066090
CAS No: 477600-70-7
Mol.F. : C14H22N2
Mol.Wt. : 218.3
Tofacitinib Impurity 42
CAT No: o2h-T066094
CAS No: NA
Mol.F. : C54H62N10O4S2
Mol.Wt. : 979.28
Tofacitinib Impurity 41
CAT No: o2h-T066093
CAS No: NA
Mol.F. : C28H44N4
Mol.Wt. : 436.69
Tofacitinib -Enantiomer intermediate
CAT No: o2h-T066092
CAS No: NA
Mol.F. : C27H31N5O2S
Mol.Wt. : 489.64
N-Nitroso Tofacitinib Impurity 2
CAT No: o2h-T066097
CAS No: NA
Mol.F. : C16H22N6O2
Mol.Wt. : 330.4
Tofacitinib N-Nitroso impurity
CAT No: o2h-T066096
CAS No: NA
Mol.F. : C13H18N6O
Mol.Wt. : 274.32
Tofacitinib Impurity 43
CAT No: o2h-T066095
CAS No: NA
Mol.F. : C32H40N12O2
Mol.Wt. : 624.75
Tofacitinib Desmethyl Nitrosamine impurity
CAT No: o2h-T066099
CAS No: NA
Mol.F. : C15H17N7O2
Mol.Wt. : 327.34
N-Nitroso Tofacitinib Impurity 3
CAT No: o2h-T066098
CAS No: NA
Mol.F. : C14H21N3O
Mol.Wt. : 247.34
