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Our clients

o2h discovery offers a broad gamut of biochemical, biophysical, and cell-based bioassay screening services for supporting drug discovery programs of our various collaborators. To augment these services, we have incorporated SPR-based assays (surface plasmon resonance) in our portfolio using state-of-the-art Biacore T200 system.

The Biacore T200 provides real-time, label-free, affinity and kinetic analysis for various types of biomolecular interactions with high sensitivity and accuracy. This system enables our team to deliver robust, high-quality data in a time-bound manner for the screening of small molecules, biologics and NBEs (novel biological entities) at any phase of drug development. We offer various project-tailored SPR solutions which include the following:

  • Fragment-based drug discovery (FBDD)
  • Small molecule drug discovery
  • Biotherapeutic drug discovery

                             SPR - Biacore

(o2h discovery – Biacore T200)

o2h biology capabilities

We accelerate time-to-market using diverse scientific teams with extensive academic and industry expertise, that are committed to resource efficiency, scientific excellence, and strategic collaborations. The expanding team of biologists in India collaborates seamlessly with the UK team to provide clients with the best solution in terms of speed, cost, and talent. o2h Biology has the infrastructure and expertise to conduct a wide range of biochemical, biophysical, and cellular assays against a wide range of target classes, including enzymes, GPCRs, and ion channels. To enable these assays, the Biology department has state-of-the-art facilities for in-vitro pharmacology services, including sophisticated liquid-handling and assay-detection systems. We are expanding our infrastructure pipeline with FLIPR penta, CytoFLEX flow cytometer, and the Integra Assist Plus liquid handler.

To know more about our biology services offering or to request our brochure, please reach out to us at discovery@o2h.com.

our team

prashant shah

Prashant Shah

CEO - o2h discovery and Co-Founder - o2h group

Prashant's Biography

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Prashant Shah

CEO - o2h discovery and Co-Founder - o2h group

Prashant is a serial entrepreneur in life sciences and tech in which one of those companies was acquired by a public company. He is currently active in seed investing (a portfolio of ~50 companies), product/IP development, services, and building lab/office infrastructure. The early career was with the Strategy group at Accenture. He has a BEng, an MSc, in which he worked on the Human Genome Program at the Sanger Centre, and an MPhil in Management from the Judge Institute. Prashant is also a General Partner in the o2h SEIS/EIS Human Health Funds.


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Sunil

Sunil Shah

CEO - o2h Ventures and Co-Founder - o2h discovery

Sunil's Biography

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Sunil Shah

CEO - o2h Ventures and Co-Founder - o2h discovery

A serial entrepreneur having begun a career in the Life Sciences team at PA Consulting group followed by co-founding two companies in the information technology and life sciences sector. The second of these companies, Oxygen Healthcare Ltd was acquired by Piramal Enterprises Ltd (BSE: PEL). Sunil co-founded o2h ventures which involves discovery services / collaborations, seeding drug discovery, academic in-licensing and biotechnology incubation. Sunil has a degree in Biochemistry and an MBA from Cambridge University


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Andy Morley

Andy Morley

Chief Scientific Officer

Andy's Biography

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Andy Morley

Chief Scientific Officer

Andy is a highly experienced and accomplished Medicinal Chemist with over 25 years of experience in major pharmaceutical companies such as Sanofi-Aventis and AstraZeneca. He has extensive experience across all phases of drug discovery and has played a key role in the development of five candidates that have reached clinical trials. Andy is a prolific author and inventor, with over 55 publications and patents to his name. Since 2013, he has been working full-time with o2h Limited, where he leads the scientific evaluation of investment opportunities and provides scientific support. He has also served as CSO for two early-stage collaborations within the o2h Ventures portfolio, demonstrating his ability to successfully guide drug discovery projects from concept to clinical development.


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David Davies - o2h

David Davies

Head of Medicinal Chemistry

David's Biography

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David Davies

Head of Medicinal Chemistry

David Davies has 25 years of experience in medicinal chemistry within the pharmaceutical industry with a focus on the antibacterial area (clavulanates, penicillinates, pseudomonates and bacterial topoisomerase inhibitors). He previously worked at GSK and currently holds a part-time academic position at University College London (UCL). He served as the Head of Medicinal Chemistry at Antabio for nearly a decade, specialising in antibacterial research, and has extensive experience managing chemistry projects in multiple countries including France, UK, India and China. He is the inventor of 40 patents and has authored 37 publications.


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o2h group launched revolutionary project management app for drug discovery

o2h group launched revolutionary project management app for drug discovery. The app’s full suite of project management tools is available exclusively to live project collaborators and a lighter version is open for researchers looking for a quote for the synthesis of small molecules.

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