We hope that you have had a good summer!
o2h discovery have been busy expanding our global collaborator base, expanding our service offering and developing our UK and Indian research capabilities and footprint. Please see a few key updates below:
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We recently launched the o2h kickstarter competition which was exclusively for early stage biotech to boost their drug discovery research. The programme aimed to extend o2h discovery’s small molecule and medicinal chemistry research expertise to seed early stage biotech companies who have innovative ideas in drug science and are planning to push it forward to the next milestones.
We have communicated information to the winners and will be feeding these amazing start-ups through our LinkedIn pages shortly. The first of which we have announced to be Alevin Therapeutics. Congratulations!
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Integrated Drug Discovery
We have always had small molecule discovery chemistry and ADME at the core of our business; over the last 24 months we have invested significantly in building our biology capabilities in Cambridge, UK and Ahmedabad, India.
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We are now running 10 fully integrated discovery projects globally. The initial premise was that we would do target validation and assay optimisation in the UK and then tech transfer to India to run the primary and secondary screening assays close to the synthetic chemistry.
Reach out to the team at discovery@o2h.com
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Biology Capabilities
Going from strength to strength, our UK Biology team has doubled in size in 2022. In keeping with this growth, the facilities at Hauxton House have recently added new instruments to expand our molecular biology capabilities and enhance our tissue culture capacity. Furthermore, with increasing demand for our high content imaging services, several upgrades are planned for our core system.
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We eagerly anticipate these hardware and software updates, which will enable parallel workflows and deliver greater access to our net >25 years’ cumulative experience in this field.
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Peptide Synthesiser
o2h discovery has an extensive experience across peptide synthesis, purification and characterisation and to leverage this experience we have added Biotiage SYRO I, fully automated multi-channel peptide synthesiser to accelerate our collaborators drug discovery programmes.
o2h discovery strong synthetic capabilities are supported by a state-of-the-art purification and analytical characterisation platform such as prep HPLC (Waters, Shimadzu, Agilent), Mass directed prep-HPLC systems (Waters) and analytical equipment includes NMR 400 MHz (Bruker), UPLC LC-MS (Waters), etc.
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Scale up
We are ready to provide process R&D and scale-up services. We also have a scale-up area with dedicated fume hoods to support “on the go” troubleshooting, hazardous reactions/distillations and all other operations. The space has been purpose-built to facilitate non-GMP scale-up synthesis.
Reach out to the team at discovery@o2h.com
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o2h discovery made its presence at...
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3rd MMCS 2022
o2h discovery sponsored as well as exhibited at the 3rd Molecules Medicinal Chemistry Symposium in Rome, Italy, from July 27-29, 2022. The conference focused on recent development in medicinal chemistry for rare diseases, and revisited drug discovery approaches, such as target and hit identification, hit-to-lead optimisation, the tuning of physicochemical and pharmacokinetic properties, preclinical and clinical development, and more.
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Claudio Dagostin, Director of Business Development represented o2h discovery in this event.
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EFMC-ISMC 2022
o2h discovery also exhibited at the XXVII EFMC International Symposium on Medicinal Chemistry which took place from September 4-8 in Nice, France. This year's EFMC-ISMC focused on major therapeutic areas such as bacterial and viral infections, with an emphasis on present and emerging viral pandemics, neurodegenerative and cardiovascular disorders.
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Andy Morley, Chief Scientific Officer along with Claudio represented o2h discovery at the conference. This was our first time exhibiting at an EFMC International Symposium.
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Pharma ChemOutsourcing 2022
o2h discovery attended Pharma ChemOutsourcing 2022. ChemOutsourcing is the largest API and Pharmaceutical Ingredients event in the United States, gathering 700-800 customers, project and executive management, and business development employees from 30 nations from the pharmaceutical, biotech, chemical, and chemistry services industries each year.
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Biotech Bootcamp
o2h co-work labs, a business unit of o2h group, launched the first ever influencer biotech bootcamp covering representatives from the quintet influencer community that are the creative forces driving biotech. The event was held at the newly renovated Hauxton House at the Mill SciTech Park, where o2h co-work labs are building a community of creators covering life-science, technology, and green innovation.
We are delighted to be back with the second edition of the influencer biotech bootcamp which will take place on the 11th and 12th of October from 9 a.m. to 2.30 p.m. An eclectic pedagogy of high intensity expert subject tours, masterclasses, personal stories, workshops, Q&A's, and debates will be part of the Bootcamp.
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Biotech Bikers
We had a terrific time hosting the BiotechBikers network ride event at Hauxton House, which was attended by a diverse group of entrepreneurs, venture capitalists, lawyers, university scientists, and biotech professionals, demonstrating the diversity and vigor of our local biotech ecosystem.
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Shirish Research Park
o2h discovery recently inaugurated Shirish Research Park in Ahmedabad, India, spread across 80,000 sq. ft. The labs will contain chemistry, biology, scale-up, ADC, and all of the skills needed to support preclinical drug development programmes, with the goal of creating an east-west ecosystem to jump-start early stage life science opportunities.
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The R&D center will provide every opportunity for fast paced collaborative drug discovery research with its modern architecture, space, cutting edge technologies and social engagement facilities. At full capacity the research center will accommodate 750+ scientists across various disciplines working on 480+ Fumes hoods spread across 25+ labs.
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Hauxton Meadows
o2h group recently acquired 40,000 sq ft Hauxton Meadows site in Cambridge, UK with plans to develop state-of-the-art co-working lab spaces for life scientists and biotech entrepreneurs in the region.
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