Programme Overview

At o2h Discovery, we recognise that reliable and fast peptide synthesis services is crucial for accelerating innovation, advancing drug discovery, and delivering life-changing therapies without delay. This is why a dependable and fast peptide synthesis service becomes essential.

With the o2h Peptide Guarantee Programme, our goal is simple: deliver high-quality peptides in 2 weeks.
If delayed, it’s on us!

This initiative is designed to accelerate the peptide drug discovery journey for small-molecule-focused biotech organisations, academic researchers, and pharma companies by providing peptides with speed, precision, and reliability. Our expertise in fast peptide synthesis services supports the development of innovative therapies that address unmet medical needs, helping advance groundbreaking science that improves human health and the environment. Also read our guide to peptide drug discovery and custom peptide synthesis.

Programme Highlights

Ultra-Fast Peptide Synthesis

High-quality peptides delivered in 2 weeks. If delayed, it’s on us.

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  • Each project will undergo a feasibility assessment before being accepted under the guaranteed peptide delivery program.
  • Upon receipt of your RFQ and/or work plan, our scientific team will conduct a technical review and a formal proposal will be shared, including:
     – Proposed synthesis routes
     – Relevant literature references
     – Key considerations
     – Estimated costs and timelines
     – Delivery terms under the o2h Peptide Guarantee programme
  • Guaranteed timelines apply to:
     – Up to 20 linear peptides with standard modifications and chain lengths of approximately 20 amino acids (via library-type synthesis), or
     – Up to 10 moderately complex peptides involving advanced modifications and requiring microwave-assisted synthesis.
  • Once the proposal is formally approved, the project team will be introduced and we will proceed with procurement of required materials.
  • The turnaround time is calculated from the date of final project confirmation and material availability. The 2-week delivery commitment applies to the production phase, excluding shipping time, and specifically refers to the synthesis turnaround time (TAT) from project initiation.
  • o2h reserves the right to determine project eligibility for the guarantee after internal review.
  • If project-specific information is required, a Confidential Disclosure Agreement (CDA) can be executed to enable open technical discussions.
  • For non-standard peptide projects that do not qualify under this initiative, the o2h team will provide a custom FFS (Fee-for-Service) proposal with a competitive quote and tailored timelines and delivery offers, subject to separate terms and conditions.

Highly Experienced Peptide Chemists

Work with our expert scientists with vast experience in synthesising and optimising complex peptide molecules with efficiency.

End-to-End Peptide Solutions

From custom synthesis and
complex modifications at mg to gram scale, to purification, analysis and characterisation; we handle it all with precision.

Cutting-Edge Equipment & Advanced Capabilities

o2h’s peptide facility is equipped with Biotage Syro I, CEM Liberty Blue, and more for fast, high-quality peptide production.

Need peptides fast? Let’s talk

About o2h Discovery

Founded in 2005, o2h Discovery has a multi-modality integrated drug discovery platform, operating from Cambridge, UK, and Ahmedabad, India. We execute hit-lead-optimisation programmes leading into patent and IND filing with expertise in discovery chemistry, biology, pharmacology, and the ongoing project management of pre-clinical development.

We have experienced scientists who deliver a comprehensive range of custom peptide synthesis services, from small quantities of a few milligrams to larger amounts at gram scale. Our capabilities go beyond standard peptide synthesis services, offering specialised peptide modification services to customise and optimise peptides for diverse drug discovery programmes. Our clients include large pharma companies, leading academic institutions, and biotech firms. We’re also available on Scientist.com.

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about o2h

Our Peptide Platform

With cutting-edge infrastructure, expert scientists, and a commitment to speed, we remove the traditional roadblocks in peptide sourcing, ensuring your research moves forward—faster than ever.

State-of-the-art facility for peptide synthesis, purification, analysis and characterisation

Expertise in traditional solution phase and advanced solid phase peptide synthesis (SPPS)

Capabilities to generate library of standard average length peptides (20-mer), as well as to deliver long chain (50-mer) and complex peptides

Peptide Range & Modifications

In addition to synthesis, our experienced team of chemists also excel in performing a wide range of peptide modifications, including but not limited to the following:

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Linear - long chain peptides

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Acetylated Peptides

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Macrocyclic Peptides

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Branched Peptides

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PEGylated Peptides

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Di-sulphide bond formation

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Succinylated Peptides

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Head to Tail Cyclization

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Lactam ring formation

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Stapled Peptides

Equipment Overview

CEM equipment

CEM - Liberty Blue

Microwave assisted synthesizer for difficult peptide synthesis including: incorporation of non-natural residues, branching, cyclization, and many more…

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Biotage Syro 1

Parallel synthesizer with robotic programming support for efficient turn around of multiple peptides in parallel or scale up of peptide of interest…

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Biotage-Syro-II

Biotage Syro 2

An automated, high-throughput, multi-channel peptide synthesizer designed for creating large peptide libraries and demanding synthesis applications…

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CEM - Liberty Blue

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Biotage Syro 1

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Biotage-Syro-II

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Analytical Suite Overview

We have an experienced team of dedicated analytical scientists and labs equipped with the latest instrument to manage and achieve high ‘speed’ delivery of peptide projects.

Analytical

LCMS

NMR(400 MHz-Bruker)

Purification

HPLC-Reverse Phase

Prep HPLC

o2h Biology Capabilities

At o2h Discovery, we offer a comprehensive suite of biology services, including FP, SPR, FRET, HCI, and flow cytometry. Our team has also validated a range of peptide-focused ADME assays, including plasma protein binding (PPB), plasma stability, and permeability studies.

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Reach out to our scientific team for expert guidance on our peptide synthesis services for your peptide drug discovery project

At o2h Discovery, we believe that open, clear communication is the foundation of every successful scientific partnership. That’s why our dedicated peptide team is always ready to engage, whether you’re exploring complex sequences, seeking rapid synthesis, or considering a new collaboration.

We offer tailored, expert-led solutions to meet your specific peptide requirements. Reach out to start the conversation, we’re here to accelerate your peptide drug discovery journey.


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    FAQs

    What makes o2h Discovery a preferred CRO partner for peptide synthesis services?

    o2h Discovery’s 2-week Peptide Guarantee ensures fast, reliable delivery of high-quality peptides. Combined with rigorous QC, global service, and expert project management, we are a trusted CRO partner for custom peptide synthesis service in drug discovery.

    How does o2h Discovery help accelerate peptide drug discovery projects?

    By delivering peptides within a guaranteed 2-week timeframe, we remove synthesis delays. This allows researchers to advance screening, validation, and pipeline development faster than with traditional peptide CRO services.

    How does o2h Discovery deliver peptides faster than other CROs?

    Through optimized workflows, dedicated resources, and an experienced chemistry team, we synthesize and deliver standard linear peptides within 2 weeks without compromising purity or reliability.

    Why should I choose o2h Discovery for my custom peptide synthesis projects?

    With o2h Discovery, you get guaranteed timelines, >95% purity, and seamless communication. Our custom peptide synthesis services help minimize risk and accelerate your drug discovery pipeline.

    Can I track the status of my peptide project with o2h Discovery?

    Yes. We provide regular progress updates throughout the synthesis process, so you always know the status of your peptide order.

    How do I submit a peptide project to o2h Discovery?

    Simply share your peptide sequence and project details via our website or email. Once confirmed, your project is placed into our guaranteed 2-week workflow.

    What is the o2h Peptide Guarantee Programme?

    It’s a global initiative by o2h Discovery offering custom peptide synthesis delivered in 2 weeks of project initiation. If delayed, it’s on us. This is designed to accelerate early-stage drug discovery by ensuring fast, high-quality, and reliable peptide delivery.

    What types of peptides are covered under the 2-week guarantee?

    Standard linear peptides up to 20 amino acids in length and up to a gram in quantity are covered under our guarantee.

    What purity levels do you provide for peptides?

    All peptides are synthesized at ≥95% purity and come with complete analytical data, including HPLC, MS, and a Certificate of Analysis (COA).

    What is the minimum and maximum scale of peptide synthesis?

    We offer flexible scales, ranging from 1 mg to gram quantities, tailored to your project requirements.

    Is the 2-week Peptide Guarantee available globally?

    Yes, the o2h Peptide Guarantee is available to biotech and pharma companies worldwide. Delivery timelines depend on customs and shipping partners.

    Can you make modified or more sophisticated peptide species, such as cyclic peptides, bi-functional/bi-valent, peptide drug conjugates, modifications such as PEGylation and PTMs, labelled peptides, and so on?

    Yes, we could make the core linear peptide under the guarantee, but the modifications would usually be outside the scope of the peptide guarantee, and we would perform this aspect under our usual service model. Please contact us to discuss how we would approach this for you.

    When does the 2-week peptide turnaround time begin?

    The 2-week turnaround time starts from the date of final project confirmation and material availability. It refers specifically to the synthesis phase and does not include shipping time.

    Are all peptide synthesis projects eligible for the 2-week guarantee?

    No, project eligibility is determined after internal review by the o2h Discovery team. Non-standard peptides or complex sequences may not qualify; in such cases, a custom Fee-for-Service (FFS) proposal will be provided with tailored timelines.

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    Speak to a member of our team

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