High-content imaging can systematically leverage information-rich microscopy data using the objective principles of algorithmic image analysis. At o2h discovery, we are equipped with the versatile Cell Insight CX7 Pro platform, with which our experienced Biology team can offer a wide variety of high-content imaging assays formats to support drug discovery projects.
We have developed high-content imaging assays for a variety of key analytical endpoints, some of which are listed below. Collectively, our team possesses decades of experience harnessing phenotypic cell biology for novel assays and we can deliver bespoke exploratory assay development and can also develop analytical solutions on a number of popular third-party software packages.
Listed examples:
- Protein trafficking
- Protein translocation and transcription factor activation
- Target recruitment into sub-cellular organelles
- Receptor internalization and endocytosis
- Cell cycle analysis, Mitotic progression and Cytokinesis
- Proliferation, apoptosis, autophagy invasiveness, drug resistance
- DNA Damage Response (DDR) and recruitment to sites of repair
- Cell health, Cell morphology changes etc.
To learn more about our phenotypic screening capabilities, click here.
To know more about our biology services offering or to request our brochure, please reach out to us at discovery@o2h.com.