From Lab Scale R&D to Large Scale Production. (gram to Kg)
In our 15+ years of experience of working on fast-paced drug discovery projects with companies across the globe, we have prepared thousands of new chemical entities. We put this experience together, along with our talented staff and high-end infrastructure, to offer high quality and cost-effective services for your ‘development’ projects.
- Route scouting for novel, cost effective and scalable route
- Process development and optimization for pre-clinical supplies
- Scale-up of intermediates, building blocks and final targets
- Analytical method development & large scale purification support
- Synthesis, isolation and characterization of process impurities
- TSE/BSE certification and Metal content analysis
- Milestone based project tracking with thorough and real time communication
- Supply of a thorough and a detailed tech pack with active assistance for technology transfer
- GMP Synthesis Support*
Reaction Technology
- 20L Glass Reactor
- 50L Glass Reactor
- 100L Glass Reactor
- 20L Rotavapour
- Hydrogenators (50/100/250mL, 1/2/5 ltrs)
- Nutsche filter & Centrifuge
- Vacuum tray dryer
- Microwave
- Lyophilizer
Analytical Capabilities
- SFC – Analytical
- NMR (400 MHz Bruker)
- LCMS
- HPLC – Reverse Phase
- HPLC – ELSD Detector
- HPLC – Chiral / Normal Phase
- GC
- LCMS/MS
- Polarimeter (SOR)
- Karl Fischer Titrator
Purification Equipment
- SFC – Preparative (mg, gm, Kg-scale)
- Scale up Flash System
- Flash System
- PREP HPLC
To know more about our scale-up services offering or to request our brochure, please reach out to us at discovery@o2h.com.